Cyclobenzaprine: MedlinePlus Drug Information
This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy.
- It should not be used by people with an overactive thyroid or who are currently or have recently used MAOIs.
- Talk to your doctor if you are using marijuana (cannabis).
- For these reasons, in the elderly, cyclobenzaprine should be used only if clearly needed.
- Because of the possibility of higher blood levels in the elderly as compared to younger adults, use of cyclobenzaprine extended-release capsules is not recommended in the elderly.
- For neck pain, however, mixed results are obtained (Peloso et al 2005).
- It is ineffective in muscle spasm due to central nervous system disease.
Cyclobenzaprine may be used as part of combination therapy. This means you may need to take it with other medications. Ask your pharmacist any questions you have about refilling your prescription. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. The best way to know how often you should be taking cyclobenzaprine is to consult your doctor and follow the directions as prescribed. Because of its effect on the brain, cyclobenzaprine can cause sleepiness and impair judgment.
Rinse the mouth to make sure all of the medicine have been swallowed. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Secondary endpoints included a physician’s evaluation of the presence and extent of palpable muscle spasm. In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward. All patients suspected of an overdose with FLEXERIL should receive gastrointestinal decontamination.
Cyclobenzaprine, oral tablet
This depends on dosage, which can affect how long your next day drowsiness lasts and how severe it is. It’s recommended to take your dose 1 to 2 hours before bed, which will decrease your chances of experiencing side effects the next day. After taking it, you should be prepared for sleep, not driving home from work or preparing a hot meal.
The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Ask your doctor before making flexeril.live any changes in how or when you take your medications. Cyclobenzaprine is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.
Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin). Physostigmine is not recommended except to treat life-threatening symptoms that have been unresponsive to other therapies, and then only in close consultation with a poison control center.
Serotonin Syndrome Associated with Cyclobenzaprine Use
That’s why it’s important to know your dosage, understand how long the effects last, and how long it stays in your system. After each tablet was split, the individual fragment weights were measured and recorded. A theoretical half-fragment weight (THW) was used to calculate percent weight and drug content ranges from the average weight of the tablets for each trial. Prior to splitting, each whole tablet was weighed on a special scale and the weight was recorded. The participants practiced the splitting technique with each device with up to four tablets; the weights of which were not included in the analysis.
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For most patients, the recommended dose of FLEXERIL is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of FLEXERIL for periods longer than two or three weeks is not recommended. Elderly patients seem to tolerate cyclobenzaprine less and may develop hallucinations as well as significant anticholinergic side effects, such as sedation. The use of significant lower dosing schedules in elderly patients may be prudent.
Although rare, deaths may occur from overdosage with FLEXERIL. Multiple drug ingestion (including alcohol) is common in deliberate cyclobenzaprine overdose. As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible. The acute oral LD50 of FLEXERIL is approximately 338 and 425 mg/kg in mice and rats, respectively.
During this time, it’s recommended to avoid drinking alcohol, operating machinery, driving, or any high performing tasks. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Abuse of muscle relaxants alone is uncommon; often, it involves other substances. Eight double-blind controlled clinical studies were performed in 642 patients comparing FLEXERIL 10 mg, diazepam, and placebo.